• Full Time
  • Randburg, Gauteng , South Africa


1 Years Fixed Term Contract



Advanced Materials Division


The candidate will join the Antibody and Antigen Production Platform. This entails working with protein expression, purification, and assays to develop antibodies and antigens for diagnostic purposes. The candidate will work with the team to manage, optimize, and run expression, purification, and assay experiments on multiple systems for validation


  • Expression, purification, and characterization of antibodies and antigens
  • Assist in identifying, developing, and validating a variety of biological assays used to support the development of tool antibodies and antigens
  • Assist in the optimization of high throughput expression, purification, and assays automation systems used to support the development of therapeutic and tool antibodies
  • Characterize assays for their throughput, strengths and weaknesses and suggest improvements or alternatives to drive innovation and continual improvements
  • Work with the process owners to run day-to-day assays and to identify areas of improvement
  • Analyze and track data over time to identify systematic errors and drift


PhD degree with relevant experience in Biochemistry, Molecular or Cell Biology, Immunology or related field


  • Strong knowledge of present and next generation antibody discovery, small scale expression, purification, and screening
  • Experience using automation systems and liquid handlers
  • Demonstrated experience with techniques used to measure antibody-antigen interaction (ie. ELISA, HTRF, AlphaScreen)
  • Knowledge of cell based assays is a plus
  • Demonstrated independence in experimental design, execution, data analysis, and troubleshooting
  • Effective communication of work, plans, and progress using written and verbal communication
  • Ability to efficiently manage and prioritize multiple projects and coordinate material exchanges with end users
  • Attention to detail with excellent organizational skills and accurate record keeping

SALARY PACKAGE: Negotiable                                  CLOSING DATE:  02 September 2020

The above-mentioned vacancy is also available on the Mintek website at

Mintek is an equal opportunity, affirmative action employer, whose aim is to promote representivity in all levels of occupational categories.


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